Influence of process parameters on properties of Nanostructured Lipid Carriers (NLC) formulation.

Influence of process parameters on properties of Nanostructured Lipid Carriers (NLC) formulation.

Nanostructured lipid carriers (NLC) are stable colloidal formulations with notable advantages for drug delivery systems. Thanks to their physicochemical stability, biocompatibility, biodegradability and controlled drug release, they have received increasing attention for the last several years. The aim of the study was to prepare and characterize nanostructured lipid carriers (NLC). Both, the e...

Itraconazol-Loaded Nanostructured Lipid Carriers (NLC) for Pulmonary Application

Formulation Optimization and Evaluation of Nanostructured Lipid Carriers Containing Valsartan

Nanostructured lipid carriers (NLCs), a lipid based colloidal carrier system, offer many advantages such as increase the solubility, improves the bioavailability and therapeutic efficacy. Incorporation of liquid lipid can improve the drug loading capacity in the NLCs. Valsartan is an antihypertensive drug with low oral bioavailability ranging from 10-35% because of poor solubility and extensive...

Optimization of Nanostructured Lipid Carrier (NLC) Formulation: Selecting the Appropriate Parameters and Components for Optimized Drug Delivery System Formulation

Effect of compositions in nanostructured lipid carriers (NLC) on skin hydration and occlusion

PURPOSE To study the effects of varying lipid concentrations, lipid and oil ratio, and the addition of propylene glycol and lecithin on the long-term physical stability of nanostructured lipid nanocarriers (NLC), skin hydration, and transepidermal water loss. METHODS The various NLC formulations (A1-A5) were prepared and their particle size, zeta potential, viscosity, and stability were analy...